CDR2 Polyclonal Antibody

CDR2 Polyclonal Antibody SKU # E-AB-11068 Reactivity Human, Mouse Host Rabbit Applications IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse Applications IHC Clonality Polyclonal Immunogen Recombinant protein of human CDR2 Abbre CDR2 Synonyms AA617262,  CDR 2,  CDR 62,  CDR2,  CDR62,  Cerebellar degeneration related protein,  Cerebellar degeneration related protein 2,  Cerebellar degeneration related protein 2 62kDa,  Cerebellar degeneration-related protein 2,  MGC,  MGC116181,  Major Yo paraneoplastic antigen Swissprot Q01850 Cellular Localization Other locations: cytoplasm. Concentration 0.4 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Immunology Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution IHC 1:50-1:200 Background CDR2 (cerebellar degeneration-related protein 2), also referred to as Yo or CDR62, is a 545 amino acid protein that is associated with the development of paraneoplastic cerebellar degeneration (PCD).PCD, an immune-mediated syndrome, belongs to a heterogeneous group of rare paraneoplastic neurologic disorders affecting the neurological system.PCD is characterized by subacute cerebellar ataxia and occurs mainly in patients with ovarian, uterine, fallopian tube or breast cancer.