CK-8 Polyclonal Antibody Store at -20°C

CK-8 Polyclonal Antibody Store at -20°C SKU # E-AB-13908 Reactivity Human,  Mouse,  Rat Host Rabbit Applications IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse,  Rat Applications IHC Clonality Polyclonal Immunogen Recombinant protein of human KRT8 Abbre CK-8 Synonyms CARD2,  CK 8,  CK-8,  CK8,  CYK8,  CYKER,  Cytokeratin endo A,  Cytokeratin-8,  DreK8,  EndoA,  K2C8,  K8,  KO,  KRT8,  Keratin,  Keratin 8,  Keratin type II cytoskeletal 8,  Keratin-8,  Krt 2.8,  MGC118110,  MGC174782,  MGC53564,  MGC85764,  Type-II keratin Kb8,  sb:cb186,  type II cytoskeletal 8 Swissprot P05787 Cellular Localization Cytoplasm Concentration 0.6 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Signal Transduction Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution IHC 1:50-1:200 Background This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.