E-Selectin Polyclonal Antibody Reactivity Human

E-Selectin Polyclonal Antibody Reactivity Human SKU # E-AB-10570 Reactivity Human Host Rabbit Applications IHC Product Details Isotype IgG Host Rabbit Reactivity Human Applications IHC Clonality Polyclonal Immunogen Recombinant protein of human SELE Abbre E-Selectin Synonyms CD26E,  CD62 antigen-like family member E,  CD62E,  E selectin,  E-selectin,  ELAM,  ELAM-1,  ELAM1,  ESEL,  Endothelial adhesion molecule 1,  Endothelial leukocyte adhesion molecule 1,  LECAM2,  LYAM2,  Leukocyte-endothelial cell adhesion molecule 2,  Sele,  Selectin E Swissprot P16581 Cellular Localization Membrane. Concentration 0.3 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Cardiovascular,  Immunology,  Stem Cells Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution IHC 1:50-1:200 Background The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.