GAS2 Polyclonal Antibody Store at -20°C

GAS2 Polyclonal Antibody Store at -20°C SKU # E-AB-10339 Reactivity Human, Mouse Host Rabbit Applications IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse Applications IHC Clonality Polyclonal Immunogen Recombinant protein of human GAS2 Abbre GAS2 Synonyms GAS 2,  GAS-2,  GAS2,  Gas2,  Growth arrest specific 2,  Growth arrest specific protein 2,  Growth arrest-specific protein 2,  MGC32610 Swissprot O43903 Cellular Localization Cytoplasm>cytoskeleton. Membrane. Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles. Concentration 0.4 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cell Biology,  Signal Transduction Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution IHC 1:25-1:100 Background The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.