OLR1 Polyclonal Antibody

OLR1 Polyclonal Antibody SKU # E-AB-10934 Reactivity Human Host Rabbit Applications IHC Product Details Isotype IgG Host Rabbit Reactivity Human Applications IHC Clonality Polyclonal Immunogen Recombinant protein of human OLR1 Abbre OLR1 Synonyms C-type lectin domain family 8 member A,  CLEC8A,  Lectin like oxLDL receptor 1,  Lectin like oxidized LDL receptor 1,  Lectin type oxidized LDL receptor 1,  Lectin-like oxLDL receptor 1,  Lectin-like oxidized LDL receptor 1,  Lectin-type oxidized LDL rece,  hLOX 1,  hLOX-1 Swissprot P78380 Cellular Localization Cell membrane. Secreted. A secreted form also exists. Concentration 0.5 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Cardiovascular,  Metabolism Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution IHC 1:50-1:200 Background This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.