TFF3 Polyclonal Antibody

TFF3 Polyclonal Antibody SKU # E-AB-10008 Reactivity Human Host Rabbit Applications IHC Product Details Isotype IgG Host Rabbit Reactivity Human Applications IHC Clonality Polyclonal Immunogen Recombinant protein of human TFF3 Abbre TFF3 Synonyms ITF,  Intestinal trefoil factor,  OTTMUSP00000021729,  P1B,  Polypeptide P1.B,  TFF3,  TFI,  TREFOIL,  Trefoil factor (intestinal),  Trefoil factor 3,  hITF,  hP1.B,  mITF Swissprot Q07654 Cellular Localization Secreted>extracellular space>extracellular matrix>apical lamina. Concentration 0.2 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Signal Transduction Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution IHC 1:50-1:200 Background Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides.They are stable secretory proteins expressed in gastrointestinal mucosa.Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium.This gene is expressed in goblet cells of the intestines and colon.This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.