SDCCAG3 Polyclonal Antibody

SDCCAG3 Polyclonal Antibody SKU # E-AB-10275 Reactivity Human, Mouse Host Rabbit Applications WB, IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse Applications WB,  IHC Clonality Polyclonal Immunogen Recombinant protein of human SDCCAG3 Abbre SDCCAG3 Synonyms Antigen NY CO 3,  NY CO 3,  NY-CO-3,  OTTHUMP00000022582,  SDCCAG 3,  Serologically defined colon cancer antigen 3 Swissprot Q96C92 Calculated MW 48 kDa Cellular Localization Cytoplasmic Concentration 0.5 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200 Background SDCCAG3 protein contains the region similar to the coiled-coil domain of the myosin tail. The same domain is present in the proteins related to the organelles/proteins trafficking, such as kinesin, Golgin-160, and dynein. SDCCAG3 function might be related to protein trafficking and secretion, May be involved in modulation of TNF response, May be involved in presentation of TNFRSF1A on the cell surface. Interaction of SDCCAG3 with the Arf GTPase activating protein GIT1 (G protein-coupled receptor kinase interactor-1). Overexpression of an ArfGAP-negative version of GIT1 also results in an increased number of multinucleate cells suggesting regulation of Arf-mediated vesicular trafficking or signaling via SDCCAG3.