E2F6 Polyclonal Antibody

E2F6 Polyclonal Antibody SKU # E-AB-10295 Reactivity Human, Mouse Host Rabbit Applications WB, IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse Applications WB,  IHC Clonality Polyclonal Immunogen Recombinant protein of human E2F6 Abbre E2F6 Synonyms E2F 6,  E2F binding site modulating activity protein,  E2F transcription factor 6,  E2F transcription factor 6 isoform 1,  E2F-6,  E2F6,  EMA,  MGC111545,  Transcription factor E2F6 Swissprot O75461 Calculated MW 32 kDa Cellular Localization Nucleus. Concentration 0.9 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Epigenetics and Nuclear Signaling Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 Background This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants.