KIF3A Polyclonal Antibody Store at -20°C

KIF3A Polyclonal Antibody Store at -20°C SKU # E-AB-10420 Reactivity Human, Mouse Host Rabbit Applications WB Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse Applications WB Clonality Polyclonal Immunogen Recombinant protein of human KIF3A Abbre KIF3A Synonyms KIF 3,  KIF 3A,  KIF3,  KIF3A,  Kif3a,  Kifl,  Kinesin family member 3A,  Kinesin family protein 3,  Kinesin family protein 3A,  Kinesin like protein KIF 3A,  Kinesin like protein KIF3A,  Kinesin-like protein KIF3A,  Kns3,  Microtubul,  Microtubule plus end directed kinesin motor 3A Swissprot Q9Y496 Calculated MW 80 kDa Cellular Localization Cytoplasm>cytoskeleton. Concentration 0.2 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Neuroscience,  Signal Transduction,  Stem Cells Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution WB 1:200-1:1000 Background Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene.Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C.KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis.KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined.Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.