PLAUR Polyclonal Antibody Store at -20°C

PLAUR Polyclonal Antibody Store at -20°C SKU # E-AB-10547 Reactivity Human, Mouse, Rat Host Rabbit Applications WB, IHC Product Details Isotype IgG Host Rabbit Reactivity Human Applications WB, IHC Clonality Polyclonal Immunogen Recombinant protein of human PLAUR Abbre PLAUR Synonyms CD 87,  CD87,  CD87 antigen,  MO 3,  MO3,  Monocyte activation antigen Mo3,  PLAUR,  Plasminogen activator receptor urokinase,  Plasminogen activator urokinase receptor,  U PAR,  U-PAR,  UPA receptor,  u plasminogen activator receptor,  u-plasminogen activator receptor form 2,  uPAR Swissprot Q03405 Calculated MW 37 kDa Cellular Localization Secreted and Cell membrane. Concentration 0.4 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Cardiovascular,  Immunology Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200 Background This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.