CDK5 Polyclonal Antibody Store at -20°C

CDK5 Polyclonal Antibody Store at -20°C SKU # E-AB-10221 Reactivity Human, Mouse, Rat Host Rabbit Applications WB, IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse,  Rat Applications WB,  IHC Clonality Polyclonal Immunogen Recombinant protein of human CDK5 Abbre CDK5 Synonyms CDK5,  Cdk 5,  Cdk5,  Cell division protein kinase 5,  Crk6,  Cyclin dependent kinase 5,  Cyclin-dependent kinase 5,  PSSALRE,  Protein kinase CDK5 splicing,  Serine threonine protein kinase PSSALRE,  Serine/threonine-protein kinase PSSALRE,  Tau protein kinase II catalytic su Swissprot Q00535 Calculated MW 33 kDa Cellular Localization Cytoplasm. Cell projection>lamellipodium. Cell projection>growth cone. In axonal growth cone with extension to the peripheral lamellipodia. Concentration 0.3 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Cell Biology,  Metabolism,  Neuroscience Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution WB 1:500-1:2000 IHC 1:25-1:100 Background Cyclin-dependent kinases (CDKs) are serine/threonine kinases that are activated by cyclins and govern eukaryotic cell cycle progression. While CDK5 shares high sequence homology with its family members, it is thought mainly to function in postmitotic neurons to regulate the cytoarchitecture of these cells. Analogous to cyclins, the regulatory subunits p35 and p39 associate with and activate CDK5 despite the lack of sequence homology.