IRAK4 Polyclonal Antibody Store at -20°C

IRAK4 Polyclonal Antibody Store at -20°C SKU # E-AB-10409 Reactivity Human, Mouse Host Rabbit Applications IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse Applications IHC Clonality Polyclonal Immunogen Recombinant protein of human IRAK4 Abbre IRAK4 Synonyms IL-1 receptor-associated kinase 4,  IPD1,  IRAK 4,  IRAK-4,  IRAK4,  IRAK4 mutated form 1,  Interleukin 1 receptor associated kinase 4 mutant form 1,  Interleukin-1 receptor-associated kinase 4,  Interleukin1 receptor associated kinase 4,  LOC 51135,  NY REN ,  NY REN 64 Swissprot Q9NWZ3 Cellular Localization Cytosol, Endosome membrane, Extracellular region or secreted, extracellular space, Nucleus, Plasma Membrane, Other locations: cytoplasm. Concentration 0.6 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Cardiovascular,  Immunology,  Signal Transduction Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution IHC 1:50-1:200 Background This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.