RETNLB Polyclonal Antibody Reactivity Human

RETNLB Polyclonal Antibody Reactivity Human SKU # E-AB-10579 Reactivity Human Host Rabbit Applications IHC Product Details Isotype IgG Host Rabbit Reactivity Human Applications IHC Clonality Polyclonal Immunogen Recombinant protein of human RETNLB Abbre RETNLB Synonyms C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 2,  CCGR,  Colon and small intestine specific cysteine rich protein,  Colon and small intestine-specific cysteine-rich protein,  Colon carcinoma,  Colon carcinoma related gene protein Swissprot Q9BQ08 Cellular Localization Secreted. Concentration 0.3 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Signal Transduction Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution IHC 1:50-1:200 Background Resistin-like betais aproteinthat in humans is encoded by theRETNLBgene. An infusion of either resistin or RELMB in rats rapidly induced severe hepatic but not peripheral insulin resistance. Increases in circulating resistin or RELMB levels markedly stimulated hepatic glucose production despite the presence of fixed physiologic insulin levels. This enhanced rate of glucose output was due to increased flux through glucose-6-phosphatase. The results supported the notion that a novel family of fat- and gut-derived circulating proteins modulates hepatic insulin action.