ANXA2 Polyclonal Antibody Store at -20°C

ANXA2 Polyclonal Antibody Store at -20°C SKU # E-AB-10043 Reactivity Human, Mouse, Rat Host Rabbit Applications WB, IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse,  Rat Applications WB,  IHC Clonality Polyclonal Immunogen Recombinant protein of human ANXA2 Abbre ANXA2 Synonyms heavy chain,  ANX 2,  ANX2,  ANX2L4,  ANXA2,  Annexin A2,  Annexin II,  Annexin-2,  CAL1H,  Calpactin I heavy chain,  Calpactin I heavy polypeptide,  Calpactin-1 heavy chain,  Chromobindin-8,  Epi,  arylsulfatase B,  calpactin I heavy polypeptide (p36),  chromobindin 8 Swissprot P07355 Calculated MW 38 kDa Cellular Localization Secreted>extracellular space>extracellular matrix>basement membrane. Melanosome. In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism. Concentration 0.4 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Signal Transduction Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution WB 1:1000-1:5000 IHC 1:25-1:100 Background This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.