CRTAM Polyclonal Antibody

CRTAM Polyclonal Antibody SKU # E-AB-10260 Reactivity Human Host Rabbit Applications WB, IHC Product Details Isotype IgG Host Rabbit Reactivity Human Applications WB,  IHC Clonality Polyclonal Immunogen Recombinant protein of human CRTAM Abbre CRTAM Synonyms CD355,  CRTAM,  Class I MHC restricted T cell associated molecule,  Class-I MHC-restricted T-cell-associated molecule,  Cytotoxic and regulatory T cell molecule,  Cytotoxic and regulatory T-cell molecule Swissprot O95727 Calculated MW 45 kDa Observed MW Refer to Figures The actual band is not consistent with the expectation. Cellular Localization Membrane. Concentration 0.3 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Immunology Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200 Background The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.