HSP105 Polyclonal Antibody

HSP105 Polyclonal Antibody SKU # E-AB-10380 Reactivity Human, Mouse, Rat Host Rabbit Applications WB Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse,  Rat Applications WB Clonality Polyclonal Immunogen Recombinant protein of human HSPH1 Abbre HSPH1 Synonyms Antigen NY CO 25,  Antigen NY-CO-25,  DKFZp686M05240,  He,  Heat shock 105kD,  Heat shock 105kD alpha,  Heat shock 105kD beta,  Heat shock 105kDa protein,  Heat shock 105kDa protein 1,  Heat shock 105kDa/110kDa protein 1,  Heat shock 110 kDa protein,  Heat shock 110kDa protein Swissprot Q92598 Calculated MW 97 kDa Cellular Localization Cytoplasm. Concentration 0.2 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Signal Transduction Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution WB 1:500-1:2000 Background Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene.Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.Inhibits HSPA8/HSC70 ATPase and chaperone activities.Highly expressed in testis.Present at lower levels in most brain regions, except cerebellum.Overexpressed in cancer cells.Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.