PPP1CB Polyclonal Antibody Store at -20°C

PPP1CB Polyclonal Antibody Store at -20°C SKU # E-AB-10548 Reactivity Human, Mouse, Rat Host Rabbit Applications WB, IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse,  Rat Applications WB,  IHC Clonality Polyclonal Immunogen Recombinant protein of human PPP1CB Abbre PPP1CB Synonyms MGC3672,  PP 1B,  PP-1B,  PP1B,  PP1beta,  PPP1CB,  PPP1CD,  Protein phosphatase 1,  Protein phosphatase 1 beta,  Protein phosphatase 1 catalytic subunit beta isoform,  Protein phosphatase 1 delta,  beta isozyme,  catalytic subunit,  de Swissprot P62140 Calculated MW 37 kDa Cellular Localization Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus. Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles. Concentration 0.3 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Metabolism,  Signal Transduction Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution WB 1:500-1:2000 IHC 1:25-1:100 Background The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.