IKK Gamma Polyclonal Antibody Store at -20°C

IKK Gamma Polyclonal Antibody Store at -20°C SKU # E-AB-10845 Reactivity Human,  Mouse,  Rat Host Rabbit Applications IHC Product Details Isotype IgG Host Rabbit Reactivity Human,  Mouse,  Rat Applications IHC Clonality Polyclonal Immunogen Recombinant protein of human IKBKG Abbre IKBKG Synonyms IkB kinase subunit gamma,  Inhibitor of nuclear factor kappa B kinase subunit gamma,  AMCBX1,  FIP 3,  FIP-3,  FIP3,  Fip3p,  I kappa B kinase gamma,  I-kappa-B kinase subunit gamma,  IkB k,  IkB kinase associated protein 1,  IkB kinase gamma subunit,  IkB kinase subunit gamma Swissprot Q9Y6K9 Cellular Localization Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress. Concentration 0.3 mg/mL Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. Purification Method Affinity purification Research Areas Cancer,  Cell Biology,  Cardiovascular,  Epigenetics and Nuclear Signaling,  Immunology,  Signal Transduction Conjugation Unconjugated Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. Related Reagents Applications Recommended Dilution IHC 1:50-1:200 Background This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways.Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies.Multiple transcript variants encoding different isoforms have been found for this gene.A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.